[Drug] Vasopressor, Inotropics

Dopamine     (Dopamine)    (400mg/250ml/bag)             è   1.6 mg/ml

mcg/kg/min		2		10		20
mcg/kg/hr		120		600		1200
mg/kg/hr		0.12		0.6		1.2
40	mg/hr mg/ml	4.8	3	24	15	48	30
50		6	4	30	19	60	38
60		7.2	4.5	36	23	72	45
70		8.4	5	42	26	84	53
80		9.6	6	48	30	96	60

Dobutamine   (Easydobu)     (250mg/250ml/bag)               è   1 mg/ml

mcg/kg/min		2.5	5	10	20
mcg/kg/hr		150	300	600	1200
mg/kg/hr		0.15	0.3	0.6	1.2
40	mg/ml	6	12	24	48
50		7.5	15	30	60
60		9	18	36	72
70		10.5	21	42	84
80		12	24	48	96

Epinephrine   (Adrenaline)   (1mg/ml/amp)                        è    1 mg/ml

                        (Bosmin)         (0.1%/500ml/bot)           è    0.5 mg/ml

1 %         = 10 mg/ml     (1:1000   = 1 mg/ml)

Norepinephrine (Levophed) (4mg/4ml/amp)

泡：2 amp in D5W 250 mlè0.03 mg/ml

mcg/min	0.5	1	2	5	10	20	30
mcg/hr	30	60	120	300	600	1200	1800
mg/hr	0.03	0.06	0.12	0.3	0.6	1.2	1.8
ml/hr	1	2	4	10	20	40	60

[Drug] Herpes Zoster (Shingles) & Varicella (ChickenPox)

Shingles

1.    Devirus       OINT         PID                            (Acyclovir 3%, for rash (esp. V1))
                                                                                (痊癒後，必須再繼續治療3天)

2.   Valtrex         2#              PO       TID  *7D        (Valacicovir 500mg)

                     or

Famvir         2#             PO       TID                 (Famciclovir 250mg) 

                     or

Acyclovir    2#              PO       TID                 (Acyclovir 400mg)

Varicella：
Acyclovir    20mg/kg/dose (max: 800mg)   PO   QID *5D

注意事項：
1. High risk group才用藥
(a) Tintinalli：Children >12 yo, adults, chronic skin or pulmonary disease, long-term salicylate therapy, immunocompromised
(b) 健保給付：
2. US-FDA沒有批准famvir或valtrex使用在varicella

Immunocompromised or CNS or Disseminated(>3 dermatome or cross midline)
Acyclovir    500 mg      IVD      Q8H                 (10~15 mg/kg/dose)

Interaction with Warfarin

P450 microsomal enzyme inhibitors: (i.e. Drugs that increase the INR and risk of bleed)

Gastrointestinal: Cimetidine, omeprazole and possibly other PPIs
Cardiovascular: Amiodarone(liver enzyme inhibition is low and may persist long after withdrawal)
Anti-fungals(azoles)
Antibiotics: Bactrim(co-trimoxazol), macrolides, metronidazole, quinolones
Anti-depresants: Fluvoxamine, SNRI,SSRI

P450 enzyme inducers: (i.e. that decrease the INR)

Anti-epileptics: carbamazepine, phenobarb, phenytoin
Rifampicin(most potent inducer)
OCP/HRT
Alcohol(Chronic)
Griseofulvin