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2013年4月6日 星期六

[自行整理] C-Spine CT Rules (NEXUS, CCR)

NEXUS Criteria (National Emergency X-radiography Utilization Study Low-Risk Criteria)       NEJM2000;343:94 –99
A patient’s neck can be clinically cleared safely without radiographic imaging if ALL 5 low-risk conditions are NEGATIVE:                            (mnemonic: NSAID)
1. Focal Neurological deficit
2. Spinal (posterior midline) tenderness
3. Altered mental status
4. Intoxication 
5. Clinically apparent, painful Distracting injury

Canadian C-spine Rules (CCR)                                                                       NEJM2003;349:2510 –2518



The Canadian C-spine rule versus the NEXUS low-risk criteria in patients with trauma.                                                                                         N Engl J Med. 2003 Dec 25;349(26):2510-8.
CCR was more sensitive than the NLC (99.4 % vs. 90.7 %, P<0.001) and more specific (45.1 % vs. 36.8 %, P<0.001) for injury, and its use would have resulted in lower radiography rates (55.9 % vs. 66.6 %, P<0.001).
In secondary analyses that included all patients, the sensitivity and specificity of CCR, assuming that the indeterminate cases were all positive, were 99.4 % and 40.4 %, respectively (P<0.001 for both comparisons with the NLC). Assuming that the CCR was negative for all indeterminate cases, these rates were 95.3 % (P=0.09 for the comparison with the NLC) and 50.7 % (P=0.001). The CCR would have missed 1 patient and the NLC would have missed 16 patients with important injuries.
Conclusion: For alert patients with trauma who are in stable condition, the CCR is superior to the NLC with respect to sensitivity and specificity for cervical-spine injury